March 11th/2021 - CALGARY, AB
Many factors influence your cow’s risk of developing subclinical milk fever. Subclinical milk fever, or more correctly called subclinical hypocalcemia, is a low blood calcium level associated with parturition in dairy cows. The cut-point for defining subclinical hypocalcemia (SCH) is most often set at a blood calcium level less than 2.1 mmol/L. The blood calcium becomes low in these cows because of the increased demand for calcium due to the onset of lactation and the shear amount of calcium required to produce colostrum and milk. And although SCH does not have any symptoms that even the most trained producers can see, it causes alterations in the health and production of the cow. SCH can lead to the development of secondary issues, such as displaced abomasum, metritis, retained placenta, ketosis, increased susceptibility to disease such as mastitis, and a decrease in milk production. Because of the lack of clinical signs, SCH cases often go unnoticed, but upon blood testing it is apparent that low blood calcium is to blame.
There are factors that increase your cow’s susceptibility to having low blood calcium following calving. First, low magnesium in the diet predisposes a cow to developing SCH. This is because magnesium is essential for calcium metabolism, parathyroid hormone secretion (the hormone that is responsible for increasing blood calcium in the body), and vitamin D metabolism (which plays a role in calcium absorption from the gut)4. Second, cows that have low blood calcium levels prior to calving are at a higher risk of developing SCH1. This accentuates the importance of testing blood calcium levels around calving, because finding cows that have a blood calcium level below 2.4 mmol/L before calving would allow for selective treatment with oral calcium boluses. Third, cows that have had more calves are at higher risk of developing SCH. Cows that have had three or more calves are 70% more likely to have SCH1. The fourth risk factor is lameness in cows, which makes them 3.2 times more likely to develop SCH than a sound cow. Lame cows treated with oral calcium boluses increased milk production, indicating that there is a link between hypocalcemia and lameness.
1. Neves, R., Leno, B., Stokol, T., Overton, T., and McArt, J. (2016). Risk factors associated with postpartum subclinical hypocalcemia in dairy cows. Journal of Dairy Science, 100: 3796-3804.
2. Chapinal, N., Carson, M., LeBlanc, S., Leslie, K., Godden, S., Capel, M., Santos, J., Overton, M., and Duffield, T. (2012). The association of serum metabolites in the transition period with milk production and early-lactation reproductive performance. Journal of Dairy Science, 95: 1301-1309.
3. Martinez, N., et al. (2012). Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease. Journal of Dairy Science, 95: 7158-7172.
4. Lean, I., DeGraris, P., McNeil, D., and Block, E. (2006). Hypocalcemia in dairy cows: Meta-analysis and dietary cation anion difference theory revisited. Journal of Dairy Science, 89: 669-684.
February 8th/2021 - Calgary, AB
Our multi-faceted device is nearing completion, and soon will be ready for mass manufacturing. CPS is in the progress of actively and aggressively seeking out manufacturing partners for the device and other components for our Milk Fever test.
January 28th/2021 - Calgary, AB
Six dairy farms in Alberta will be visited by our very own DVM Sjoert Zuidhof in order to conduct our final field trial to collect data and finalize our product design requirements in anticipation of the imminent launch of CPS' newest product - Calciulate.
January 21st/2021 - Calgary AB
CPS recently became a member of BioAlberta. BioAlberta is a member-driven association that represents and promotes the province's vibrant and diverse life sciences industry.
January 16/2021 - Calgary, AB
CPS has hired a new Business Development Manager to help with the growth of the business, corporate finances, manufacturing scale up, and the many other various tasks associated with the role. Tyler Desormeaux is an MBA candidate at the University of Calgary, and will graduate in June.
January 5/2021 - Calgary, AB
CPS has added to the team in anticipation of a busy year ahead. Sjoert Zuidhof, MBA, DVM, will be working on contract for CPS as he finishes up some of his other commitments. We are thrilled to have him join our team with his breadth of experience and hope to have him as a full time employee soon.
December 1/2020 - Calgary, AB
CPS has closed its latest round of financing that was initiated back in March of 2020. This raise will be a great help to our market launch. We welcome our newest investor Draper University Ventures (DUV). We look forward to their mentorship and appreciate their belief in the vision of CPS.