Point-of-care tests

Our trehalase‐based biosensor platform offers a versatile and convenient method for point‐of‐care applications as it does not require sample preparation or handling and can be integrated with existing glucometers or sensors.

Our electrochemical (EC) point-of-care biosensors will revolutionize companion and production animal medicine, as they can accurately and inexpensively diagnose animal diseases at home or on the farm.

CPS has integrated the TreAsure Assay reagents with EC sensing and mobile technology for highly sensitive, selective, and rapid point-of-care sensing of biomarkers of chronic and infectious diseases. Disposable test strips detect these biomarkers in a single drop of blood or milk. Immediate and quantified results are acquired with a small handheld device which transmits the results to your cell phone.

Our POC device and test strips are currently in demo mode only. Contact us to learn more.

  • Bovine Colostrum or Serum IgG (immunoglobulin G)

Currently, there are no on-farm tools that directly measure immunoglobulin (IgG) content in colostrum or serum. Our developed Split Trehalase IgG quantification Assay (STIGA), explained under lab tests, can already be used in a user-friendly on-farm format (STIGAField). A fully integrated POC solution for on-farm IgG quantification is under development.

STIGAField  uses pre-assembled freeze-dried reagents and a commercially available handheld glucometer. This format does not require any assembly of test, but only application of the diluted sample; hence, it eliminates the need for laboratory equipment and specifically trained personnel.

  • Mastitis

We are developing disposable pen-side tests and a simple portable reader for pen-side detection of lactoferrin (LF), a mastitis biomarker. The lactoferrin level in milk is a good indicator of clinical and subclinical mastitis. A strong correlation exists between pathogen numbers in milk and the level of lactoferrin. Importantly, LF concentrations in milk are alo significantly positively correlated with somatic cell counts (SCC), with increases in LF concentration preceding the SCC increases. 

  • Milk fever

A very sensitive blood calcium concentration  test was developed accurate for  calcium quantification. This assay can be used to detect low calcium levels in clinical or subclinical cases of milk fever.

  • Inflammation

If you are suffering from an inflammatory disease, your doctor might order a CRP test or monitoring scheme to check for inflammation, which can indicate infection or a chronic disease, such as rheumatoid arthritis or lupus, as well as risk of heart disease. Normally, this will require multiple visits to a professional health center for blood collections. Instead, we propose a much more convenient solution, whereby you can measure CRP levels in a pin-prick of blood at home, with single-use test strips, a simple device and a cell phone app which transmits your results directly to your health care professional.